Top 7 Runeword Combinations

Introduction: This guide teaches the top seven runeword combinations. The best Ritual runes and Invocation runes can be found before the Best 7 Runeword Combinations section. Runewords are made by combining a Ritual rune and an Invocation rune in a two socketed piece of equipment. Ritual runes are similar to trigger runes that gain 'offering' and once you have enough offering an additional effect or skill is cast by the Invocation rune. The best Ritual rune for a runeword varies depending on which trigger is the best for your build.

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Best Ritual Runes:

 

1. Cir, Neo, Igni, Bac, Tam, and Nagu are the 7 best Ritual Runes and which ones you use in runewords will vary based on your build.

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Best Invocation Runes:

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1. Vex is the best Invocation Rune for all builds that are +skill dependent because it can give up to +3 to all skills.

2. Ohm is a high cost pure damage option for builds that already have enough defenses or builds that don't take high damage.

3. Wat is a defensive rune which no longer executes enemies but it casts Decrepify which slows enemies and lowers their damage.

4. Eom lowers all of your cooldowns by 0.1 seconds and is useful on builds that have several cooldown skills.

5. Kry is used for Vortex to deal damage and group enemies together for builds that need enemies grouped together for damage.

6. Yom triggers Petrify which stuns enemies and generates primary resources but it also has the drawback of having a 500 offering cost.

7. Thul no longer provides Vulnerability as of season 13 but it's still strong defensively with its Frost Nova which freezes enemies.

8. Now on to the Best 7 Runeword Combinations...

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The Best 7 Runeword Combinations Guide:

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1. CirVex (300/100)

Cir requires you to cast five skills for its offering and Vex increases your plus skills by three because of the triple offering bonus.

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2. NeoOhm (200/600), IgniOhm (25/600), TamOhm (25/600), or BacOhm (50/600)

Neo requires you to not take damage for 2 seconds, Igni stores offering and releases it when you use a non-basic skill, Tam triggers with Core skills, and Bac requires you to move 5 meters. Ohm is used to trigger a War Cry that increases your damage by 15% for 6 seconds.

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3. NeoWat (200/100), IgniWat (25/100), TamWat (25/100), or BacWat (50/100)

Neo requires you to not take damage for two seconds, Igni stores offering every 0.3 seconds which is released when you use a non-basic skill, Tam triggers on Core Skills, and Bac requires you to move 5 meters. The Wat Invocation rune releases the Necromancer Decrepify curse on enemies which slows enemies and reduces their damage.

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4. NeoEom (200/100), IgniEom (25/100), TamEom (25/100), or BacEom (50/100)

Neo requires you to not take damage for 2 seconds, Igni stores offering which is released when you use a non-basic skill, Tam triggers on core skills, and Bac requires you to move 5 meters. The Eom rune is used to repeatedly reduce all of your cooldowns by 0.1 seconds.

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5. NeoKry (200/300), CirKry (300/300), IgniKry (25/300), TamKry (25/300), or BacKry (50/300)

Neo requires you to not take damage for two seconds, Cir requires you to cast five skills, Igni stores offering which is released when you use a non-basic skill, and Bac requires you to move 5 meters. Kry is used to group enemies together with Vortex and it deals damage.

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6. NeoYom (200/500), IgniYom (25/500), TamYom (25/500), or BacYom (50/500)

Neo requires you to not take damage for two seconds, Igni stores offering every 0.3 seconds which is gained when you use a non-basic skill, Tam triggers with Core skills and is great for builds that use Core skills, and Bac requires you to move 5 meters. Yom triggers Petrify which stuns enemies and generates primary resources which is great offensively and defensively for builds that use resources.

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7. NeoThul (200/300), IgniThul (25/300), TamThul (25/300), or BacThul (50/300)

Neo requires you to not take damage for two seconds, Cir requires you to cast five skills and then has a cooldown, Igni stores offering every 0.3 seconds which is gained when you use a non-basic skill, Tam triggers with Core skills and is great for builds that spam Core skills, and Bac requires you to move 5 meters. Thul releases a Frost Nova that freezes nearby enemies and makes them Vulnerable.

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And that's all for the Best 7 Runewords Guide. You can find more about Diablo 4 in the menu at the top of this page. Good luck!

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